| 1 | Brazilian Grand Prix | 3rd Apr 1988 | Autódromo Internacional Nelson Piquet
Rio de Janeiro, Brazil | Alain Prost (McLaren) |
| 2 | San Marino Grand Prix | 1st May 1988 | Autodromo Enzo e Dino Ferrari
Imola, Italy | Ayrton Senna (McLaren) |
| 3 | Monaco Grand Prix | 15th May 1988 | Circuit de Monaco
Monte-Carlo, Monaco | Alain Prost (McLaren) |
| 4 | Mexican Grand Prix | 29th May 1988 | Autódromo Hermanos Rodríguez
Mexico City, Mexico | Alain Prost (McLaren) |
| 5 | Canadian Grand Prix | 12th Jun 1988 | Circuit Gilles Villeneuve
Montreal, Canada | Ayrton Senna (McLaren) |
| 6 | Detroit Grand Prix | 19th Jun 1988 | Detroit Street Circuit
Detroit, USA | Ayrton Senna (McLaren) |
| 7 | French Grand Prix | 3rd Jul 1988 | Circuit Paul Ricard
Le Castellet, France | Alain Prost (McLaren) |
| 8 | British Grand Prix | 10th Jul 1988 | Silverstone Circuit
Silverstone, UK | Ayrton Senna (McLaren) |
| 9 | German Grand Prix | 24th Jul 1988 | Hockenheimring
Hockenheim, Germany | Ayrton Senna (McLaren) |
| 10 | Hungarian Grand Prix | 7th Aug 1988 | Hungaroring
Budapest, Hungary | Ayrton Senna (McLaren) |
| 11 | Belgian Grand Prix | 28th Aug 1988 | Circuit de Spa-Francorchamps
Spa, Belgium | Ayrton Senna (McLaren) |
| 12 | Italian Grand Prix | 11th Sep 1988 | Autodromo Nazionale di Monza
Monza, Italy | Gerhard Berger (Ferrari) |
| 13 | Portuguese Grand Prix | 25th Sep 1988 | Autódromo do Estoril
Estoril, Portugal | Alain Prost (McLaren) |
| 14 | Spanish Grand Prix | 2nd Oct 1988 | Circuito de Jerez
Jerez de la Frontera, Spain | Alain Prost (McLaren) |
| 15 | Japanese Grand Prix | 30th Oct 1988 | Suzuka Circuit
Suzuka, Japan | Ayrton Senna (McLaren) |
| 16 | Australian Grand Prix | 13th Nov 1988 | Adelaide Street Circuit
Adelaide, Australia | Alain Prost (McLaren) |