| Round | Race | Date | Circuit | Winner |
|---|---|---|---|---|
| 1 | Monaco Grand Prix | 1959-05-10 | Circuit de Monaco Monte-Carlo, Monaco | Jack Brabham (Cooper-Climax) |
| 2 | Indianapolis 500 | 1959-05-30 | Indianapolis Motor Speedway Indianapolis, USA | Rodger Ward (Watson) |
| 3 | Dutch Grand Prix | 1959-05-31 | Circuit Park Zandvoort Zandvoort, Netherlands | Jo Bonnier (BRM) |
| 4 | French Grand Prix | 1959-07-05 | Reims-Gueux Reims, France | Tony Brooks (Ferrari) |
| 5 | British Grand Prix | 1959-07-18 | Aintree Liverpool, UK | Jack Brabham (Cooper-Climax) |
| 6 | German Grand Prix | 1959-08-02 | AVUS Berlin, Germany | Tony Brooks (Ferrari) |
| 7 | Portuguese Grand Prix | 1959-08-23 | Monsanto Park Circuit Lisbon, Portugal | Stirling Moss (Cooper-Climax) |
| 8 | Italian Grand Prix | 1959-09-13 | Autodromo Nazionale di Monza Monza, Italy | Stirling Moss (Cooper-Climax) |
| 9 | United States Grand Prix | 1959-12-12 | Sebring International Raceway Florida, USA | Bruce McLaren (Cooper-Climax) |