| 1 | Bahrain Grand Prix | 2021-03-28 | Bahrain International Circuit
Sakhir, Bahrain | Lewis Hamilton (Mercedes) |
| 2 | Emilia Romagna Grand Prix | 2021-04-18 | Autodromo Enzo e Dino Ferrari
Imola, Italy | Max Verstappen (Red Bull) |
| 3 | Portuguese Grand Prix | 2021-05-02 | Autódromo Internacional do Algarve
Portimão, Portugal | Lewis Hamilton (Mercedes) |
| 4 | Spanish Grand Prix | 2021-05-09 | Circuit de Barcelona-Catalunya
Montmeló, Spain | Lewis Hamilton (Mercedes) |
| 5 | Monaco Grand Prix | 2021-05-23 | Circuit de Monaco
Monte-Carlo, Monaco | Max Verstappen (Red Bull) |
| 6 | Azerbaijan Grand Prix | 2021-06-06 | Baku City Circuit
Baku, Azerbaijan | Sergio Pérez (Red Bull) |
| 7 | French Grand Prix | 2021-06-20 | Circuit Paul Ricard
Le Castellet, France | Max Verstappen (Red Bull) |
| 8 | Styrian Grand Prix | 2021-06-27 | Red Bull Ring
Spielberg, Austria | Max Verstappen (Red Bull) |
| 9 | Austrian Grand Prix | 2021-07-04 | Red Bull Ring
Spielberg, Austria | Max Verstappen (Red Bull) |
| 10 | British Grand Prix | 2021-07-18 | Silverstone Circuit
Silverstone, UK | Lewis Hamilton (Mercedes) |
| 11 | Hungarian Grand Prix | 2021-08-01 | Hungaroring
Budapest, Hungary | Esteban Ocon (Alpine F1 Team) |
| 12 | Belgian Grand Prix | 2021-08-29 | Circuit de Spa-Francorchamps
Spa, Belgium | Max Verstappen (Red Bull) |
| 13 | Dutch Grand Prix | 2021-09-05 | Circuit Park Zandvoort
Zandvoort, Netherlands | Max Verstappen (Red Bull) |
| 14 | Italian Grand Prix | 2021-09-12 | Autodromo Nazionale di Monza
Monza, Italy | Daniel Ricciardo (McLaren) |
| 15 | Russian Grand Prix | 2021-09-26 | Sochi Autodrom
Sochi, Russia | Lewis Hamilton (Mercedes) |
| 16 | Turkish Grand Prix | 2021-10-10 | Istanbul Park
Istanbul, Turkey | Valtteri Bottas (Mercedes) |
| 17 | United States Grand Prix | 2021-10-24 | Circuit of the Americas
Austin, USA | Max Verstappen (Red Bull) |
| 18 | Mexico City Grand Prix | 2021-11-07 | Autódromo Hermanos Rodríguez
Mexico City, Mexico | Max Verstappen (Red Bull) |
| 19 | São Paulo Grand Prix | 2021-11-14 | Autódromo José Carlos Pace
São Paulo, Brazil | Lewis Hamilton (Mercedes) |
| 20 | Qatar Grand Prix | 2021-11-21 | Losail International Circuit
Al Daayen, Qatar | Lewis Hamilton (Mercedes) |
| 21 | Saudi Arabian Grand Prix | 2021-12-05 | Jeddah Corniche Circuit
Jeddah, Saudi Arabia | Lewis Hamilton (Mercedes) |
| 22 | Abu Dhabi Grand Prix | 2021-12-12 | Yas Marina Circuit
Abu Dhabi, UAE | Max Verstappen (Red Bull) |